Something rare nowadays – a publication

As life continues after my years of research in R&D, there are and will be less and less publications. Therefore I am even more so excited and happy if I can contribute to some great scientific work.

Alf Claesson, the main author, and I have published a “Perspective” in the ACS journal Chemical Research in Toxicology, titled “Systematic Approach to Organizing Structural Alerts for Reactive Metabolite Formation from Potential Drugs”.

We believe it should be a good tool for especially medicinal chemists who design new compounds, but also for metabolic biologists who work with reactive metabolites. It has to do to some extend with the software SpotRM+ by Awametox which is to a certain extent the engine behind this paper.

Here is the full citation:

Systematic Approach to Organizing Structural Alerts for Reactive Metabolite Formation from Potential Drugs

Alf Claesson and Alexander Minidis
Chemical Research in Toxicology 2018 31 (6), 389-411

DOI: 10.1021/acs.chemrestox.8b00046

And the link:
https://pubs.acs.org/doi/10.1021/acs.chemrestox.8b00046