My name is Alexander Minidis, Ph.D. in organic chemistry, with a specialty in medicinal chemistry and a burning interest in data mining and linking IT with research. That, and working in general cross-functionally is something I found most intriguing in my working life so far. Lately, the hype around AI hasn’t gone past me either!
I studied (organic) chemistry in Basel, Switzerland and did my Ph.D with Professor Andreas Pfaltz in Basel and continued at the Max-Planck-Institute (MPI) f. Kohlenforschung in Mülheim, Germany. After a Post-Doc with Prof. Donna Blackmond at the MPI followed by a Post-Doc with Prof. Jan Bäckvall in Stockholm, Sweden, I started my industry career at the chemistry CRO Syntagon, Södertälje (Sweden). Missing research, I went to AstraZeneca R&D and became a medicinal chemist. There I continued working as team- and project leader. Over the years I had the opportunity to “dabble” in all sorts of activities, be it synthesis in the lab, data-mining, designing new molecules, writing patent applications, due diligence of new projects or CROs. This, combined with my latter experience, gives me a rather unique background of someone who was worked actively (not only by reading or collaboration) with nearly all aspects of pre-clinical drug research.
After the closure of AstraZeneca research unit two companions and I founded a start-up, Evomedicon AB, a company within drug research and project management. One of the things we were working with was the experience we garnered from our AZ time where we implement lean into research. Interesting to note is, that lean and scrum were (still is) disliked by many researchers, though if you simply take away the naming, one will notice that for efficient workflows lean is more or less already in place. Thus, if adapted specifically for research, lean and scrum can work! Anyway, after 2 years we decided though to close the company and follow other avenues. I continued with research at the Karolinska Institute for some years, using my industry background in an academic setting in the group of Prof. Taipale. Though I required a lot of new know-how regarding biochemical methodologies unknown to me as chemist, the thing required most was data-mining and even programming.
This lead me to support Chemnotia AB in their request to develop a software for analysis of chemical synthesis pathways of larger proteins, an ideal scenario for acting as interface as both, software person and researcher in the same person and in collaboration with the customers.
Shortly after this, I joined Collaborative Drug Design (CDD) as sort of a technical expert for the European “time-zone”, supporting internal and external customers with the main product, CDD Vault, an online database for pharmaceutical drug development. The job included a wide variety of tasks, all from writing knowledgebase articles, tutorial videos, demo-ing the software and setting it up for customers, as well handling enhancement requests, bug-hunting, or giving presentations at conferences.
After an offer by Medivir AB, I worked for a short period as application scientist & data-analyst, supporting researchers with new implementations as well as support for existing software systems – until Medivir announced closure of their R&D portion just two months into this new position. Not waiting what will happen there next, I applied and was recruited by RISE AB, Process and Development where I am working as Chemist/Project Leader. There I am working on development and potential implementation of reaction prediction methods.
Finally, I have done some occasional consulting work, two of the main customers are Awametox and Chemnotia, whom I support(ed) with QA work or data-mining/programming. This concept of being able to support others from home has evolved into this website!
Further details regarding my CV can be found on my LinkedIn profile.
My GitHub repo isn’t that large, but has a few data/chemistry related repos.
Disclaimer: The topics & opinions on this web page are my own and are not representative of any of the companies mentioned here, nor of any of my former employers. This blog and website is independent of PharmaKarma-Consulting (despite being the same physical person behind the consulting part).